Tissue Engineering Specialist

Career

Tissue Engineering Specialist

We are looking for a tissue engineering specialist to join Explicell’s interdisciplinary R&D team and take part in delivering the CUSTOMED project within IPCEI Med4Cure.

Košice Place of work

Full-time Employment

ASAP / by agreement Start

from €2,000 Base salary (gross)

The exact amount will be agreed individually, depending on the selected candidate’s professional experience, knowledge and competencies.

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Duties and responsibilities

The CUSTOMED project brings together digital processing of patient data, personalised design, biomaterials development, biofabrication, biological seeding, testing and validation. Tissue engineering and the development of biological models are an important part of its proposed architecture.

Your role will be to design and develop cell and tissue models for the biological seeding, cultivation and maturation of scaffolds and bioprinted constructs. The work will also include defining experimental protocols, biological quality attributes and acceptance criteria.

Your work will mainly include:

• Designing strategies for the biological seeding of scaffolds

• Selecting suitable cell types and culture conditions

• Developing and optimising 2D and 3D cell cultures

• Preparing scaffolds and seeding them with cells

• Designing and carrying out tissue engineering experiments

• Optimising cell adhesion, proliferation and differentiation

• Evaluating the biocompatibility of materials and the cellular response

• Monitoring cell viability and the maturation of tissue constructs

• Evaluating the differentiation and functional properties of cells

• Defining biological quality attributes and acceptance criteria

• Evaluating, interpreting and documenting experimental results

• Collaborating with experts in biomaterials, biofabrication, quality and regulatory affairs

Who we are looking for

Education

A master’s or doctoral degree in biology, biotechnology, molecular or cell biology, biomaterials, biomedical engineering, tissue engineering or another relevant field.

What we expect

• 3 to 5 years of hands-on laboratory experience relevant to the position
• Practical experience with culturing cells under 2D or 3D conditions
• Knowledge of or experience in tissue engineering, regenerative medicine, biomaterials or scaffold systems
• Experience with evaluating cell viability, adhesion, proliferation, differentiation or maturation
• Experience with at least some of the methods such as microscopy, histology, qPCR or flow cytometry
• Experience with viability and cytotoxicity assays
• Knowledge of aseptic technique, biosafety and working according to SOPs
• The ability to design experimental protocols and define control and reference samples
• The ability to plan experiments, evaluate biological data and interpret results
• A thorough approach to keeping laboratory and experimental documentation
• Analytical and systematic thinking
• Independence and responsibility for assigned tasks and outputs
• The ability to work in an interdisciplinary R&D team
• A proactive approach to communication and problem-solving

Nice to have

• Experience with bioreactors used for dynamic cell culture or tissue maturation
• Experience with bioreactors for bone or cartilage tissue
• Knowledge of microphysiological systems or organ-on-a-chip platforms
• Experience with 3D bioprinting of cells and bioinks
• Experience with preparing and biologically evaluating bioinks
• Knowledge of the rheological properties of hydrogels and their effect on cell behaviour
• Experience with the statistical evaluation of biological data
• Experience with preparing samples for histological evaluation
• Experience with defining biological quality attributes and acceptance criteria
• Experience with working with Quality Assurance and Regulatory Affairs teams
• Experience with preparing technical and experimental documentation supporting regulatory submissions
• Knowledge of GLP, GMP or another regulated laboratory environment

What we offer

1. Direct involvement in delivering the CUSTOMED project within IPCEI Med4Cure, focused on developing solutions in personalised medicine

2. Work with the latest technologies and innovative solutions in tissue engineering, biomaterials, cell cultures and 3D bioprinting

3. The opportunity to take part in developing biological models and tissue constructs with potential use in medicine

4. Work in an interdisciplinary environment, in collaboration with experts from biological, technical and medical fields

5. Room for professional growth, independence and initiative, including the opportunity to influence the experimental procedures and biological quality criteria of the solutions being developed

6. A stable working background, a modern working environment and technological equipment

7. The opportunity to attend professional conferences, training and company events

Interested?

Tissue Engineering Specialist

mbartikova@explicell.sk

Send your CV

Career 3

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All positions

Contact

Discuss Your Patient Case or Partnership

Tell us what you are planning. If you have CT or DICOM scans, mention it in your message and we will agree on a secure way to share them.

Sales and customer support

info@explicell.sk

Explicell s.r.o.

Popradská 56/D
040 11 Košice, Slovakia

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