Research Scientist: RNAi Formulations
- Location
- Lexington, United States
- Work mode
- On-site
- Type
- Contract
- Seniority
- Mid-level
- Salary
- $35–39 / hour
- Posted
- 28 Oct 2026
Verified open 2 Nov 2026 · Source: Company careers page
About the role
Research Scientist: RNAi Formulations - Contract - Lexington, MALooking to be the heartbeat of medical research? Join our client as a Research Scientist and assist in turning innovative science into life-changing care!Proclinical is seeking an Associate Research Scientist for RNAi Formulations to be focused on hands-on RNAi formulation development. Primary Responsibilities:This position will also focus on biophysical and analytical characterization as well as support the oligonucleotide delivery activities for injectable therapeutics. Skills & Requirements:MS with approximately 3 years of relevant experience, or PhD with 1-3 years of relevant experience in pharmaceutical sciences, formulation sciences, chemical engineering, biophysics, analytical chemistry, oligonucleotide delivery, or a related discipline.Hands-on experience with oligonucleotide or antibodies/proteins formulation and characterization is strongly preferred.Experience developing or running analytical methods for solubility, viscosity, osmolality, aggregation, , stability, or other developability assessments for complex oligonucleotide or antibody/protein formulations.Familiarity with automation, high-throughput screening, and DoE-based formulation optimization is an advantage.Strong experimental planning, documentation, data analysis, and problem-solving skills.Excellent verbal and written communication skills, with the ability to work effectively across disciplines and functions.Awareness of external trends and advances in RNA delivery, oligonucleotide therapeutics, and clinical translation is a plus.A track record of scientific contributions, publications, or conference presentations in relevant areas is a plus. The Research Scientist's responsibilities will be:Support the development and characterization of preclinical RNAi and oligonucleotide formulations across portfolio and platform projects.Execute hands-on formulation preparation, biophysical characterization, analytical testing, and data analysis to support formulation selection and developability assessments.Establish and run screening assays for oligonucleotides in early discovery, including formulation performance, solubility, viscosity, osmolality, degradation, , and stability assessments.Contribute to high-throughput and design-of-experiments approaches for formulation optimization, where applicable.Support long-term storage and stability evaluations for RNAi conjugates and oligonucleotide formulations.Maintain accurate experimental documentation and communicate findings through written summaries, reports, and internal presentations.Collaborate with internal stakeholders and external partners to support project deliverables and timelines.Identify technical gaps, propose practical solutions, and contribute to continuous improvement of formulation and characterization workflows.Thrive in a multidisciplinary, fast-paced research environment with competing priorities and tight deadlines. Compensation:$35 to $39 per hour. If you are having difficulty in applying or if you have any questions, please contact Shannon Briggs at s.briggs@proclinical.com If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.Proclinical is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. Proclinical is acting as an Employment Agency in relation to this vacancy.By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data - https://www.proclinical.com/privacy-policy
Skills
- RNAi
- Oligonucleotide formulation
- Protein formulation
- Biophysical characterization
- Analytical method development
- Solubility assessment
- Viscosity measurement
- Osmolality
- Aggregation analysis
- Stability studies
- Design of Experiments (DoE)
- High-throughput screening
- Data analysis
- Scientific writing
- Laboratory automation
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